Saturday, February 27, 2010

What You Need To Know About Diabetes

INTRODUCTION

According to the World Health Organization, a few decades back diabetes was an uncommon disease, in both developed and developing countries. Today, the story is different. It is currently estimated that over 143million people worldwide are affected by the disease. This figure is ever increasing, by 2020 over 220million people are expected to be living with diabetes, if the current trend continues.

In the United States alone, there are 18.2 million people (6.3% of the population) living with diabetes. While another 13million people have been diagnosed with diabetes. Unfortunately, 5.2milion (or nearly one third) are unaware that they have the disease.

The figure for Nigeria is not readily available, but it is estimated that over 1.5million people have diabetes in Nigeria.

In developed countries, most patients of diabetes are over sixty, but in developing countries, diabetes is found to affect people in their prime.

WHAT IS DIABETES?

Diabetes Mellitus (or simply diabetes) is derived from the Greek word ‘Diabeinein’, meaning ‘To pass through’ describing copious urination, and Mellitus from the Latin word meaning ‘Sweetened with honey’. These two words signify sweetened urine or sugar in urine.

Diabetes is a disease in which the body does not produce or properly use Insulin. Insulin is a hormone that is needed, in the body, to control the rate at which sugar, starch and other food are converted into glucose required as energy for daily life. The hormone is produced and released
into the blood by an organ called ‘Pancreas’. This insulin help to maintain the blood glucose level within a normal range. The World Health Organization (WHO) puts this normal range between
60 – 100mg/dl (Before taking any food for the day, hence this value is called Fasting Blood Glucose). In health, despite several demands for glucose in different situations, the blood glucose rarely exceeds this value.

After a meal the liver stores the glucose from the meal as glycogen and releases it into the blood in between meals. The role of insulin is the control of this storage and release of glucose. It ensures that the amount of glucose in the blood at every particular time does not go beyond or below the normal range.

TYPES OF DIABETES.

According to the World Health Organization (WHO), five classes of diabetes are recognized, these are; Insulin Dependent Diabetes Mellitus (IDDM) or Type I Diabetes, Non Insulin Dependent Diabetes Mellitus (NIDDM) or Type II Diabetes, Gestational Diabetes, Diabetes Insipidus and Bronze Diabetes.

INSULIN DEPENDENT/TYPE I DIABETES: This type of diabetes was initially called Juvenile onset diabetes because it affects adolescents and young adults. It is caused by a sudden failure of the pancreas to produce Insulin. It is, therefore, an acute disease, presenting with thirst, polyuria (passing large amount of urine), diuresis and weight loss. Type I diabetes is not common, it accounts for less than 10% of all diabetes cases.

NON-INSULIN DEPENDENT/ TYPE II DIABETES: This is the most prevalent type of diabetes, accounting for more than 80% of all diabetic cases. It is found in adults and the elderly. This type of diabetes develops gradually over a long period of time (unnoticed) and is characterized by insufficient insulin, deficient insulin in the blood or the inability of the body to utilize the insulin resent (Insulin resistance). Because of its slow and gradual occurrence, it is mostly undetected until one or more of its long-term complications appear.

Unlike in Type I Diabetes, the Insulin in the blood of a Type II diabetic may be normal or even high, but lacks the desired effect, due to insulin resistance, and this is prevalent among obese people.

GESTATIONAL DIABETES: This type of diabetes occurs during pregnancy and disappears after delivery, within 3weeks. An estimated 3% of all pregnancies are accompanied by gestational diabetes and almost half of these patients are prone to developing permanent diabetes later in life.
WHAT CAUSES DIABETES.

As with hypertension and other non communicable diseases, no clear cut cause(s) can be attributed to the most prevalent type of diabetes (Type II Diabetes, Type I diabetes being secondary to failure of the pancreas). However, some factors are known to increase one’s chances of becoming diabetic and these are called risk factors. For example, indolent and well-fed populations are 2 – 20times more likely to develop type II diabetes than active and lean population of the same race. Some other factors known to increase one chances of getting diabetes include:

OBESITY: It is estimated that three quarter (¾) of all Type II diabetes patient are obese. Indolent and affluent lifestyles tend to contribute to this. It is believed that a 10kg loss of weight can reduce fasting blood sugar level by almost 50md/dl. An active lifestyle with frequent exercise is also known to increase Insulin sensitivity.

The International standard for measuring overweight and obesity is based on a value called BODY MASS INDEX (BMI). This value is derived by dividing the body weight (in Kilograms) by the square of height (in metres).

i.e. BMI = Body weight (Kg) / Height2 (Metres).

Note: 1ft = 0.305metres.

For adults, a BMI less than 25kg/m2 is preferred.

25 – 29kg/m2 is considered overweight and above 30kg/m2 is Obesity.

FAMILY HISTORY: A family history of diabetes increases one’s chances of getting the disease. In such a situation, leading a healthy lifestyle and constant monitoring of one’s blood sugar level becomes very important.
AGE AND RACE: Most Type II diabetes patient are over 40yrs at presentation of the disease. However, the proportion of increase in the incidence of this disease with age is higher for those with a family history of diabetes, obese and probably those leading sedentary lifestyles. Moreover, diabetes tends to be more prevalent among Africans, African Americans, Latinos, Native Americans and Asian Americans. Belonging to any of the races is a risk factor in itself.

HISTORY OF GESTATIONAL DIABETES: in a woman also increases her chances/possibility of developing permanent diabetes later in life.

YOU CAN PREVENT/DELAY DIABETES!
Diabetes have no permanent cure once it develops, it is managed al through life. But you can prevent ever falling into this life long pain. Before diabetes present in people, it is almost always preceded by a situation called PRE DIABETES. A situation where the blood glucose is higher than normal, but not yet enough to be diagnosed as diabetes. Saddening, however, you cannot know when you fall into this category, if you have not being monitoring your blood glucose regularly.

Pre Diabetes is itself a serious medical situation, though can still be reversed by making changes in diet pattern and increasing physical activity. To determine one’s blood sugar a test called Fasting Blood Glucose has to be conducted. This test measures the amount of glucose (sugar) in one’s blood before taking any meal for the day. It is measured in milligrams per deciliter (mg/dl).

A value below 100mg/dl is generally accepted to be normal, while a value greater than 100mg/dl but less than 120mg/dl is not full diabetes yet, so it is regarded as Pre diabetes. An individual with a pre diabetes blood glucose level need to take urgent steps to reduce his blood glucose or risk life long diabetes.

It should be emphasized, however, that the racial and genetic factors predisposing to diabetes are still beyond human comprehension and control. It makes common sense, therefore, to reduce all human controllable factors to the barest minimum. Most of these factors have to do with social occupational and diet habits.

The following tips can help reduce your diabetes risk:

* Reduce weight. Obesity seems to be the single most significant factor in diabetes. Reducing body weight and fat and maintaining an average body weight is very essential. To this end a body mass index (BMI) less than 25kg/m2 for males and less than 24kg/m2 for females is recommended.

* Increase Physical Activity. It is an established fact that diabetes is more common among people that lead a sedentary affluent lifestyle. Simple dynamic exercises like brisk walking for 30-50mins daily or 3-5times weekly has been shown to be very helpful. Exercise reduces bodyweight and fat, increases functionality of the heart, reduces the chances of diabetes and also boosts emotions and healthy living.

* Cut down or cut out alcohol. Alcoholic intake of more than 2units per day has been shown to adversely affect the body. Alcohol being an addictive drug makes it very difficult to maintain a definite amount of intake for a long time. It is better therefore to strive to cut out alcohol completely.

* Avoid Smoking. Cigarette smoke has been shown to contain several poisonous substances. Cigarette smoking and alcohol have been related to several disease. Stopping smoking will definitely reduce the chances of several other ailments apart from diabetes.

* Lean good eating habits, such as;

* Cut down on fatty food and junks

* Eat more of fish and poultry (without the skin is better).

* Garlic reduces blood pressure cholesterol; add it to your meal plan once in a while.

* Cut the number of eggs you take to 3- 4 weekly (better boiled than fried).

* Reduce salt intake to less than 5.8grams daily.

* Eat more of vegetables and fibre rich food, especially fruits.

* Finally, constantly monitor your fasting blood glucose, as this is the only way to know when you are getting into trouble.

CONCLUSION

Diabetes and Hypertension being so interlinked requires a comprehensive plan of care, and this revolves round one’s dietary habits, social and environmental factors. Several lifestyle changes like regular exercise, maintaining a moderate body weight, reduction of fat intake and high fibre diet all help to live a normal healthy life. These measures are known to increase insulin sensitivity and also reduce blood pressure.

Conclusively, it is very important to create a more health conscious individuals in the populace. A people who practically believe that it is better and cheaper to prevent an illness than to treat it, when it has become stronger. Moreover, preventive health cannot be divorced from regular medical checks, as this two go hand in hand. There is no way to detect several non-communicable diseases without undergoing regular medical checks. The importance of these checks cannot be over emphasized.
Be alive to your health. Know your Blood glucose values and live a healthier life free from the pains of diabetes.

Mr. Adefemi Kazeem is a graduate of Human Anatomy from a Nigerian University and who wishes to specialize in Public Health, soon. You can contact him by e-mail – yemupz@yahoo.com; Phone – 234-803-613-6741.

Diabetes And The Long Term Dangers

Diabetes has hidden dangers that begin before diagnosis and continue to worsen if certain steps are not taken to prevent the complications that are the true, “killers” in terms of diabetes.

Statistics show that there are around 18 million diabetics in America, both Type 1 and Type 2. It is amazing how many people, diabetics included, who have no idea what dangers a diabetic faces over their lifetime. A diabetic, all things being equal, lives almost 10 years less than their non-diabetic counterpart on average.

Why do diabetics life shorter life spans than non-diabetics? The answer is both simple and complicated. Simple in explaining in general terms, complicated in the medical sense. Without traveling the complicated route in this article, I will try to give a simple, straight forward answer to the above question. Diabetics live shorter lives than non-diabetics because of diabetic complications.

What Are Diabetic Complications?

Diabetic complications are chronic medical conditions that begin to affect the body of the diabetic. These complications are brought about mostly by a condition the medical community had named, “Advanced Glycation End products” which is simply, “excess sugar” saturating the inside of the cells of the body. This condition also called AGE for short includes coronary artery disease, vascular disease, blindness, kidney disease, retinopathy (blindness) and loss of feeling in the hands and the feet (peripheral neuropathy) among others.

Diabetes in the early stages does not produce symptoms. Unless found during a routine medical exam, it is possible for a diabetic to remain undiagnosed for years. It is during these years that the beginnings of diabetic complications can gain a foothold due excess sugar in the cells (AGE). The statistics show there is the possibility of as many as over 5 million people going about their normal lives while having undiagnosed diabetes.

Are Diabetic Complications A Certainty?

While the current consensus is that the formula for diabetic complications Diabetes + Time = Complications. What this means is there is a much higher potential of a diabetic becoming diagnosed with one or more diabetic complications over time. This is partly due to how well the individual monitors and controls his/her blood sugar.

Drastic rises and falls of blood sugar can be hard on the body and the excess sugar present in the cells create havoc on the different nerves within the body as well as the capillaries, veins, and arteries. The evidence to date show that excellent control of blood sugar and an active lifestyle goes a very long way in preventing and/or slowing down the onset of diabetic complications.

The Different Types Of Diabetes

There are two types of diabetes - Type One and Type Two. Type One attacks children and young adults and is characterized by the pancreas failing to produce insulin which is a hormone that breaks down sugars and starches while converting them into energy. Type Two occurs usually later in an adult’s life and is characterized by the pancreas being unable to produce enough insulin due to several factors, obesity being one of them.

Around 10 percent of diabetics are Type One while the other 90 percent are Type Two. The major difference between the two being that Type One diabetics are completely dependent on insulin and take daily injections while the Type Two’s have both those who require insulin shots while others can rely on oral medication and/or changes in diet and exercise.

The Risk Factors Surrounding Diabetes

There are several risk factors that can push a pre-diabetic into full blown diabetes.

1) being overweight.

2) family history of diabetes,

3) lack of adequate exercise.

4) history of gestational diabetes (occurs during pregnancy and usually disappears after delivery).

5) certain ethnic groups

People over 45 years of age and has one or several of the risk factors mentioned above should be screened for diabetes each year, preferably during an annual medical exam. It has been shown that people with these risk factors comprise the majority of diagnosed cases of diabetes each year.

What Tests Help Diagnose Diabetes Cases?

There are two, main tests used for determining whether or not a person has a glucose intolerance:

1) Fasting Plasma Glucose Test

2) Oral Glucose Tolerance Test

Both of these tests can determine glucose intolerance which is where blood sugar is higher than what is considered normal. This is not always an indication of diabetes however.

Can The Onset Of Diabetes Be Prevented?

People with the above risk factors can go a long way toward preventing the development of full-blown diabetes by making significant lifestyle change. What are lifestyle changes? Changing unhealthy diets to more blood sugar friendly ones, doing enough exercise to help offset increased blood sugar levels and keep the body healthy and losing weight especially if considered obese by the medical community.

If you are pre-diabetic you need to stay on a strict diabetic diet. Ask your healthcare professional for a diet that meets that criteria and limit cakes, candy, cookies, and other things made of simple sugars. Eat small, nutritious meals and eat 5 times a day instead of only three.

If you are already diagnosed with full-blown diabetes, you should follow the same diet while under the meticulous care of your healthcare professional. Keep your cholesterol, blood pressure and blood sugar within proper limits and have your eyes checked every year.

Diabetes can contribute to blindness, kidney disease and heart disease. Complications caused nearly 70,000 deaths in 2000.

What Can The Diabetic Look Forward To?

Diabetic complications can be prevented or lessened for a longer time period by paying serious attention to lifestyle. A diabetic who eats right, keeps his blood sugar in control and within accepted limits, exercises and gets proper rest can expect to have a quality of life that is much higher in terms of the pain and suffering that diabetic complications brings into the lives of diabetics who do nothing to change their lifestyle.

What begins to occur in the diabetic who starts to develop complications because of uncontrolled blood sugars over time is a life filled with the possibility of becoming an invalid, either blind, an amputee, or suffering renal failure or a heart attack.

The above paints a rather grim picture if lifestyle changes are not adhered to. Research has shown that the diabetic that keeps their blood sugar within acceptable limits and follows a healthy, diabetic lifestyle that has been shown to be effective against diabetic complications stands a much better chance of not developing many of the complications their less than dedicated counterparts do.

There is a new derivative of thiamine (Vitamin B1) available now that is showing great promise in greatly reducing the excess sugar in the cells of the diabetic, the process known as Advanced Glycation Endproducts (AGE).

Is Benfotiamine Effective Against Diabetic Complications?

Benfotiamine is a lipid soluble derivative of thiamine. Japanese researchers developed benfotiamine in the 1950’s and later patented it in the United States in 1962. No one in the US medical community paid much attention to it at the time. For the past 12 years in Europe it has been used for neuropathy, retinopathy and other uses.

The chemical name and formula for benfotiamine is: S-benzoylthiamine-O-monophosphate (C19H23N4O6PS). It wasn’t until a group of researchers in New York at the Albert Einstein College of Medicine of Yeshiva University released the results of their research in 2003 in Nature Medicine Magazine did the rest of the world begin to take a look at this substance.

Benfotiamine is unique and was reported by Michael Brownlee, M.D., as showing much promise in preventing nerve and blood-vessel damage in diabetics. Every diagnosed diabetic has been told by his/her healthcare provider that diabetic complications are the true killers in terms of diabetes.

If you are a diabetic or know a diabetic, you may find additional information about benfotiamine and view research that has been recently conducted showing the benefits of preventing diabetic complications by following the link to the website below.

Zach Malott is CEO of Brentwood Health International, a nutritional supplement company involved in distribution and supplying wholesale, retail and end users.

Mr. Malott is available to discuss the research as it applies to benfotiamine in terms of diabetic complications such as neuropathy and retinopathy.